Genetic counseling and predictive testing for colorectal cancer risk
نویسندگان
چکیده
منابع مشابه
Risk Assessment, Genetic Counseling, and Genetic Testing for BRCA-Related Cancer in Women.
BACKGROUND Mutations in breast cancer susceptibility genes (BRCA1 and BRCA2) are associated with increased risks for breast, ovarian, and other types of cancer. PURPOSE To review new evidence on the benefits and harms of risk assessment, genetic counseling, and genetic testing for BRCA-related cancer in women. DATA SOURCES MEDLINE and PsycINFO between 2004 and 30 July 2013, the Cochrane Cen...
متن کاملGenetic counseling in hereditary nonpolyposis colorectal cancer.
Recent identification of gene mutations responsible for hereditary nonpolyposis colorectal cancer (HNPCC) has made possible the presymptomatic diagnosis of at-risk family members. If DNA testing shows that a family member is a gene carrier, that individual's lifetime cancer risk is approximately 90%. If the test is negative, the family member's cancer risk drops to that of the general populatio...
متن کاملRisk Assessment, Genetic Counseling, and Genetic Testing for BRCA-Related Cancer in Women: USPSTF Recommendation Statement
Methods: The USPSTF reviewed the evidence on risk assessment, genetic counseling, and genetic testing for potentially harmful BRCA mutations in asymptomatic women with a family history of breast or ovarian cancer but no personal history of cancer or known potentially harmful BRCA mutations in their family. The USPSTF also reviewed interventions aimed at reducing the risk for BRCArelated cancer ...
متن کاملCorrelates of intentions to obtain genetic counseling and colorectal cancer gene testing among at-risk relatives from three ethnic groups.
OBJECTIVES An understanding of factors associated with interest in genetic counseling and intentions to obtain colorectal cancer susceptibility testing is an important foundation for developing education, counseling, and genetic services and policies. MATERIALS AND METHODS A survey was mailed to first-degree relatives of patients diagnosed with colorectal cancer. The respondents (n = 426, 77%...
متن کاملGenetic counseling and testing in families with hereditary nonpolyposis colorectal cancer.
BACKGROUND Genetic testing to refine cancer risk is available. However, little is known about factors affecting the uptake of testing for the most common hereditary colon cancer, hereditary nonpolyposis colorectal cancer. This study investigated attitudes, intentions, and uptake of genetic testing within newly identified families with hereditary nonpolyposis colorectal cancer. METHODS Cohort ...
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ژورنال
عنوان ژورنال: International Journal of Cancer
سال: 1996
ISSN: 0020-7136,1097-0215
DOI: 10.1002/(sici)1097-0215(19960220)69:1<53::aid-ijc13>3.3.co;2-f